The first of a brand new class of antibiotics called oxyzolidinones, this agent has very broad activity against Gram-positive bacteria via a novel anti-ribosomal action. It was released to great “fanfare” as the solution to MRSA and VRE infections but resistance has already been described in both organisms. Its cost has ensured that it is judiciously used in Canada – $70.00 per tablet twice a day or $1400.00 for a 10 day course.